In Silico Upper Extremity Simulator
The broad goal of this program is to develop a computational framework for modelling shoulder function in both healthy people and those with shoulder dysfunction. This includes developing anatomical models of shoulder anatomy across the population, and models of bony and soft tissue mechanics in activities of daily life and after injury and surgery. These models will then be adapted for designing shoulder implants, planning shoulder surgeries, and clinical decision-making.
“Investigation on patient-specific features of shoulder MSK modelling. Study of an MRI-based EMG-driven model." Max is doing his PhD through the ARCITTC-JB at QUASR/QUT. His expertise is in the analysis of soft tissues actions implied in shoulder stability and motion. Computational modelling as well as human kinematics and EMG recordings are the key tools he works with. His project focuses on studying the influence of patient-specific modelling features on the joint simulations.
"Evaluation of proximal humerus bone density on implant fixation in Shoulder Arthroplasty" Xiaolong is our PhD student in shoulder biomechanics at QUT. He takes a multidisciplinary approach that encompasses the modelling and experiment to support surgery selecting suitable implant for independent patients basic on CT image. He holds master’s degree from QUT which focused on understanding of biomechanical properties of red kangaroo shoulder humeral cartilage.’
Dr Bart Bolsterlee is a mechanical and biomedical engineer with specific expertise in imaging and biomechanical modelling of the human musculoskeletal system. During his PhD he developed and evaluated tools for computational modelling of the human upper limb. As a postdoctoral researcher at NeuRA, he pioneered methods to reconstruct and quantify the three-dimensional architecture of human skeletal muscles from magnetic resonance and diffusion tensor imaging data.
Robotic (in vitro) Upper Extremity Simulators
Research areas of focus:
This program will use robots and emerging ultrasound technologies for studying the bone and joint response to complex three-dimensional and time-varying loads experienced during physical activity. These technologies will be used for developing robot-assisted procedures for improving precision in current shoulder arthroplasty procedures and will enable in-vitro testing of orthopaedic devices for the assessment of current and novel orthopaedic devices. This will assist surgical methods for optimal joint function and precision tracking in human motion experiments for rehabilitation and the comprehensive assessment of clinical intervention.
Scaffold Simulator: Optimization of engineered scaffolds for improved scaffold integration, tissue growth, repair and functional regeneration
This program will utilise the multiscale computational models and simulation outputs and detailed characterisation and mapping of shoulder joint biomechanics to inform the design, development, optimisation and validation of engineered scaffolds for rotator cuff repair. The integration of underlying biochemical and biomechanical cues associated with de novo tissue generation within the shoulder joint into bespoke designed, biomechanically-matched, engineered scaffolds will significantly improve upon the current empirical process applied to developing tissue scaffolds for interfacial musculoskeletal tissues (such as the rotator cuff). Thiswill further inform how tissue generation in these scaffolds can be enhanced through fit-for-purpose rehabilitation post-surgery to encourage functional tissue repair and improve patient outcomes.
In vivo assessment of upper limb movements, physiology and rehabilitation
Research areas of focus:
This program will create a functional movement database that encompasses objective multilevel measures of joint and segmental motion (kinematics and kinetics) and muscular activation. This will provide an essential multidimensional reference for design of implants, the evolution of new surgical procedures, the shaping of post-surgical rehabilitation, and evaluation of treatment success. This program will improve the understanding around biomechanical and physiological basis of upper limb movement to allow for biomechanically consistent and individualised rehabilitation exercises.
Professor Kirsten Heimann
Connect, Educate & train (CET)
Intellectual Property and Commercialisation
The MB-CRC’s prime objective is to provide a cooperative platform to accelerate the translation of marine bioproduct discoveries and create an energetic and expansive bio-economy industry in Australia, through adoption of the MB-CRC’s IP, processes and candidate products.